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A plasmid-based system for expressing small interfering RNA libraries in mammalian cells

BACKGROUND: RNA interference (RNAi) is an evolutionarily conserved process that functions to inhibit gene expression. The use of RNAi in mammals as a tool to study gene function has rapidly developed in the last couple of years since the discovery that the function-inhibiting units of RNAi are short...

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Detalles Bibliográficos
Autores principales: Kaykas, Ajamete, Moon, Randall T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416474/
https://www.ncbi.nlm.nih.gov/pubmed/15119963
http://dx.doi.org/10.1186/1471-2121-5-16