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Protein co-translocational unfolding depends on the direction of pulling

Protein unfolding and translocation through pores occurs during trafficking between organelles, protein degradation and bacterial toxin delivery. In vivo, co-translocational unfolding can be affected by the end of the polypeptide that is threaded into the pore first. Recently, we have shown that co-...

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Detalles Bibliográficos
Autores principales: Rodriguez-Larrea, David, Bayley, Hagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164780/
https://www.ncbi.nlm.nih.gov/pubmed/25197784
http://dx.doi.org/10.1038/ncomms5841