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Amino Acid Sequence and Structural Comparison of BACE1 and BACE2 Using Evolutionary Trace Method
Beta-amyloid precursor protein cleavage enzyme 1 (BACE1) and beta-amyloid precursor protein cleavage enzyme 2 (BACE2), members of aspartyl protease family, are close homologues and have high similarity in their protein crystal structures. However, their enzymatic properties differ leading to dispara...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164807/ https://www.ncbi.nlm.nih.gov/pubmed/25254246 http://dx.doi.org/10.1155/2014/482463 |