Cargando…

Amino Acid Sequence and Structural Comparison of BACE1 and BACE2 Using Evolutionary Trace Method

Beta-amyloid precursor protein cleavage enzyme 1 (BACE1) and beta-amyloid precursor protein cleavage enzyme 2 (BACE2), members of aspartyl protease family, are close homologues and have high similarity in their protein crystal structures. However, their enzymatic properties differ leading to dispara...

Descripción completa

Detalles Bibliográficos
Autores principales: Mirsafian, Hoda, Mat Ripen, Adiratna, Merican, Amir Feisal, Mohamad, Saharuddin Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164807/
https://www.ncbi.nlm.nih.gov/pubmed/25254246
http://dx.doi.org/10.1155/2014/482463