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Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria

BACKGROUND: Malaria, caused by Plasmodium sp. parasites, is a leading cause of global morbidity and mortality. Cerebral malaria, characterized by neurological symptoms, is a life-threatening complication of malaria affecting over 500,000 young children in Africa every year. Because of the prevalence...

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Detalles Bibliográficos
Autores principales: Baccarella, Alyssa, Huang, Brian W, Fontana, Mary F, Kim, Charles C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164820/
https://www.ncbi.nlm.nih.gov/pubmed/25192715
http://dx.doi.org/10.1186/1475-2875-13-354