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Chromosome length and perinuclear attachment constrain resolution of DNA intertwines

To allow chromosome segregation, topoisomerase II (topo II) must resolve sister chromatid intertwines (SCI) formed during deoxynucleic acid (DNA) replication. How this process extends to the full genome is not well understood. In budding yeast, the unique structure of the ribosomal DNA (rDNA) array...

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Detalles Bibliográficos
Autores principales: Titos, Iris, Ivanova, Tsvetomira, Mendoza, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164948/
https://www.ncbi.nlm.nih.gov/pubmed/25225337
http://dx.doi.org/10.1083/jcb.201404039