Cargando…
Amplification of Tau Fibrils from Minute Quantities of Seeds
[Image: see text] The propagation of Tau pathology in Alzheimer’s disease (AD) is thought to proceed through templated conversion of Tau protein into fibrils and cell-to-cell transfer of elongation-competent seeds. To investigate the efficiency of Tau conversion, we adapted the protein misfolding cy...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165214/ https://www.ncbi.nlm.nih.gov/pubmed/25153692 http://dx.doi.org/10.1021/bi501050g |