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Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus

Tonic inhibition mediated by extrasynaptic GABA(A) receptors (GABA(A)Rs) is an important regulator of neuronal excitability. Phosphorylation by protein kinase C (PKC) provides a key mode of regulation for synaptic GABA(A)Rs underlying phasic inhibition; however, less attention has been focused on th...

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Detalles Bibliográficos
Autores principales: Bright, Damian P, Smart, Trevor G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165308/
https://www.ncbi.nlm.nih.gov/pubmed/24102973
http://dx.doi.org/10.1111/ejn.12352