Osmoprotectants suppress the production and activity of matrix metalloproteinases induced by hyperosmolarity in primary human corneal epithelial cells

PURPOSE: Hyperosmolarity has been recognized as a proinflammatory stress in the pathogenesis of dry eye disease. This study investigated the suppressive effect of osmoprotectants (L-carnitine, erythritol, and betaine) on the production and activity of matrix metalloproteinases (MMPs) in primary huma...

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Detalles Bibliográficos
Autores principales: Deng, Ruzhi, Su, Zhitao, Hua, Xia, Zhang, Zongduan, Li, De-Quan, Pflugfelder, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165325/
https://www.ncbi.nlm.nih.gov/pubmed/25352733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165325/
https://www.ncbi.nlm.nih.gov/pubmed/25352733

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