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Non-targeted transcription factors motifs are a systemic component of ChIP-seq datasets

BACKGROUND: The global effort to annotate the non-coding portion of the human genome relies heavily on chromatin immunoprecipitation data generated with high-throughput DNA sequencing (ChIP-seq). ChIP-seq is generally successful in detailing the segments of the genome bound by the immunoprecipitated...

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Detalles Bibliográficos
Autores principales: Worsley Hunt, Rebecca, Wasserman, Wyeth W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165360/
https://www.ncbi.nlm.nih.gov/pubmed/25070602
http://dx.doi.org/10.1186/s13059-014-0412-4