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Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs

BACKGROUND: The incomplete understanding of disease causes and drug mechanisms of action often leads to ineffective drug therapies or side effects. Therefore, new approaches are needed to improve treatment decisions and to elucidate molecular mechanisms underlying pathologies and unwanted drug effec...

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Detalles Bibliográficos
Autores principales: Vogt, Ingo, Prinz, Jeanette, Campillos, Mónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165361/
https://www.ncbi.nlm.nih.gov/pubmed/25276232
http://dx.doi.org/10.1186/s13073-014-0052-z