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Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs
BACKGROUND: The incomplete understanding of disease causes and drug mechanisms of action often leads to ineffective drug therapies or side effects. Therefore, new approaches are needed to improve treatment decisions and to elucidate molecular mechanisms underlying pathologies and unwanted drug effec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165361/ https://www.ncbi.nlm.nih.gov/pubmed/25276232 http://dx.doi.org/10.1186/s13073-014-0052-z |