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MBASED: allele-specific expression detection in cancer tissues and cell lines

Allele-specific gene expression, ASE, is an important aspect of gene regulation. We developed a novel method MBASED, meta-analysis based allele-specific expression detection for ASE detection using RNA-seq data that aggregates information across multiple single nucleotide variation loci to obtain a...

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Detalles Bibliográficos
Autores principales: Mayba, Oleg, Gilbert, Houston N, Liu, Jinfeng, Haverty, Peter M, Jhunjhunwala, Suchit, Jiang, Zhaoshi, Watanabe, Colin, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165366/
https://www.ncbi.nlm.nih.gov/pubmed/25315065
http://dx.doi.org/10.1186/s13059-014-0405-3