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MBASED: allele-specific expression detection in cancer tissues and cell lines
Allele-specific gene expression, ASE, is an important aspect of gene regulation. We developed a novel method MBASED, meta-analysis based allele-specific expression detection for ASE detection using RNA-seq data that aggregates information across multiple single nucleotide variation loci to obtain a...
Autores principales: | Mayba, Oleg, Gilbert, Houston N, Liu, Jinfeng, Haverty, Peter M, Jhunjhunwala, Suchit, Jiang, Zhaoshi, Watanabe, Colin, Zhang, Zemin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165366/ https://www.ncbi.nlm.nih.gov/pubmed/25315065 http://dx.doi.org/10.1186/s13059-014-0405-3 |
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