Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia

BACKGROUND: Aberrant energy metabolism is a hallmark of cancer. To fulfill the increased energy requirements, tumor cells secrete cytokines/factors inducing muscle and fat degradation in cancer patients, a condition known as cancer cachexia. It accounts for nearly 20% of all cancer-related deaths. H...

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Detalles Bibliográficos
Autores principales: Shukla, Surendra K, Gebregiworgis, Teklab, Purohit, Vinee, Chaika, Nina V, Gunda, Venugopal, Radhakrishnan, Prakash, Mehla, Kamiya, Pipinos, Iraklis I, Powers, Robert, Yu, Fang, Singh, Pankaj K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165433/
https://www.ncbi.nlm.nih.gov/pubmed/25228990
http://dx.doi.org/10.1186/2049-3002-2-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165433/
https://www.ncbi.nlm.nih.gov/pubmed/25228990
http://dx.doi.org/10.1186/2049-3002-2-18

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