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Selective Mitogen Activated Protein Kinase Activity Sensors through the Application of Directionally Programmable D Domain Motifs

[Image: see text] Accurate and quantitative methods for measuring the dynamic fluctuations of protein kinase activities are critically needed as diagnostic tools and for the evaluation of kinase-targeted inhibitors, which represent a major therapeutic development area in the treatment of cancer and...

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Detalles Bibliográficos
Autores principales: Peterson, Laura B., Yaffe, Michael B., Imperiali, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165445/
https://www.ncbi.nlm.nih.gov/pubmed/25153342
http://dx.doi.org/10.1021/bi500862c