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Folding-Upon-Binding and Signal-On Electrochemical DNA Sensor with High Affinity and Specificity

[Image: see text] Here we investigate a novel signal-on electrochemical DNA sensor based on the use of a clamp-like DNA probe that binds a complementary target sequence through two distinct and sequential events, which lead to the formation of a triplex DNA structure. We demonstrate that this target...

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Detalles Bibliográficos
Autores principales: Idili, Andrea, Amodio, Alessia, Vidonis, Marco, Feinberg-Somerson, Jacob, Castronovo, Matteo, Ricci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165453/
https://www.ncbi.nlm.nih.gov/pubmed/24947124
http://dx.doi.org/10.1021/ac501418g