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Folding-Upon-Binding and Signal-On Electrochemical DNA Sensor with High Affinity and Specificity
[Image: see text] Here we investigate a novel signal-on electrochemical DNA sensor based on the use of a clamp-like DNA probe that binds a complementary target sequence through two distinct and sequential events, which lead to the formation of a triplex DNA structure. We demonstrate that this target...
Autores principales: | Idili, Andrea, Amodio, Alessia, Vidonis, Marco, Feinberg-Somerson, Jacob, Castronovo, Matteo, Ricci, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165453/ https://www.ncbi.nlm.nih.gov/pubmed/24947124 http://dx.doi.org/10.1021/ac501418g |
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