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Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition
[Image: see text] Feedback regulation plays a crucial role in dynamic gene expression in nature, but synthetic translational feedback systems have yet to be demonstrated. Here we use an RNA/protein interaction-based synthetic translational switch to create a feedback system that tightly controls the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165468/ https://www.ncbi.nlm.nih.gov/pubmed/23651072 http://dx.doi.org/10.1021/sb200005w |