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Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition

[Image: see text] Feedback regulation plays a crucial role in dynamic gene expression in nature, but synthetic translational feedback systems have yet to be demonstrated. Here we use an RNA/protein interaction-based synthetic translational switch to create a feedback system that tightly controls the...

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Detalles Bibliográficos
Autores principales:	Stapleton, James A., Endo, Kei, Fujita, Yoshihiko, Hayashi, Karin, Takinoue, Masahiro, Saito, Hirohide, Inoue, Tan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165468/ https://www.ncbi.nlm.nih.gov/pubmed/23651072 http://dx.doi.org/10.1021/sb200005w

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