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Synthesis and Preclinical Characterization of [(18)F]FPBZA: A Novel PET Probe for Melanoma

Introduction. Benzamide can specifically bind to melanoma cells. A (18)F-labeled benzamide derivative, [(18)F]N-(2-diethylaminoethyl)-4-[2-(2-(2-fluoroethoxy) ethoxy)ethoxy]benzamide ([(18)F]FPBZA), was developed as a promising PET probe for primary and metastatic melanoma. Methods. [(18)F]FPBZA was...

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Detalles Bibliográficos
Autores principales: Wu, Shih-Yen, Huang, Shih-Pin, Lo, Yen-Chen, Liu, Ren-Shyan, Wang, Shyh-Jen, Lin, Wuu-Jyh, Shen, Chih-Chieh, Wang, Hsin-Ell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165567/
https://www.ncbi.nlm.nih.gov/pubmed/25254219
http://dx.doi.org/10.1155/2014/912498