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The TNF-Family Cytokine TL1A Promotes Allergic Immunopathology through Group 2 Innate Lymphoid Cells

The TNF-family cytokine TL1A (TNFSF15) costimulates T cells and promotes diverse T-cell dependent models of autoimmune disease through its receptor DR3. TL1A polymorphisms also confer susceptibility to inflammatory bowel disease. Here we find that allergic pathology driven by constitutive TL1A expre...

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Detalles Bibliográficos
Autores principales: Meylan, Françoise, Hawley, Eric T., Barron, Luke, Barlow, Jillian L., Penumetcha, Pallavi, Pelletier, Martin, Sciumè, Giuseppe, Richard, Arianne C., Hayes, Erika T., Gomez-Rodriguez, Julio, Chen, Xi, Paul, William E., Wynn, Thomas A., McKenzie, Andrew N.J., Siegel, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165592/
https://www.ncbi.nlm.nih.gov/pubmed/24368564
http://dx.doi.org/10.1038/mi.2013.114