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Radiobiological Determination of Dose Escalation and Normal Tissue Toxicity in Definitive Chemoradiation Therapy for Esophageal Cancer()

PURPOSE: This study investigated the trade-off in tumor coverage and organ-at-risk sparing when applying dose escalation for concurrent chemoradiation therapy (CRT) of mid-esophageal cancer, using radiobiological modeling to estimate local control and normal tissue toxicity. METHODS AND MATERIALS: T...

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Detalles Bibliográficos
Autores principales: Warren, Samantha, Partridge, Mike, Carrington, Rhys, Hurt, Chris, Crosby, Thomas, Hawkins, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier, Inc 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165721/
https://www.ncbi.nlm.nih.gov/pubmed/25304796
http://dx.doi.org/10.1016/j.ijrobp.2014.06.028