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Reduced Cortical Complexity in Children with Prader-Willi Syndrome and Its Association with Cognitive Impairment and Developmental Delay

BACKGROUND: Prader-Willi Syndrome (PWS) is a complex neurogenetic disorder with symptoms involving not only hypothalamic, but also a global, central nervous system dysfunction. Previously, qualitative studies reported polymicrogyria in adults with PWS. However, there have been no quantitative neuroi...

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Detalles Bibliográficos
Autores principales: Lukoshe, Akvile, Hokken-Koelega, Anita C., van der Lugt, Aad, White, Tonya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165760/
https://www.ncbi.nlm.nih.gov/pubmed/25226172
http://dx.doi.org/10.1371/journal.pone.0107320