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Impact of Multiple Negative Charges on Blood Clearance and Biodistribution Characteristics of (99m)Tc-Labeled Dimeric Cyclic RGD Peptides
[Image: see text] This study sought to evaluate the impact of multiple negative charges on blood clearance kinetics and biodistribution properties of (99m)Tc-labeled RGD peptide dimers. Bioconjugates HYNIC-P6G-RGD(2) and HYNIC-P6D-RGD(2) were prepared by reacting P6G-RGD(2) and P6D-RGD(2), respectiv...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166031/ https://www.ncbi.nlm.nih.gov/pubmed/25144854 http://dx.doi.org/10.1021/bc500309r |