Two Rapid Catalyst-Free Click Reactions for In Vivo Protein Labeling of Genetically Encoded Strained Alkene/Alkyne Functionalities

[Image: see text] Detailed kinetic analyses of inverse electron-demand Diels–Alder cycloaddition and nitrilimine-alkene/alkyne 1,3-diploar cycloaddition reactions were conducted and the reactions were applied for rapid protein bioconjugation. When reacted with a tetrazine or a diaryl nitrilimine, st...

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Detalles Bibliográficos
Autores principales: Kurra, Yadagiri, Odoi, Keturah A., Lee, Yan-Jiun, Yang, Yanyan, Lu, Tongxiang, Wheeler, Steven E., Torres-Kolbus, Jessica, Deiters, Alexander, Liu, Wenshe R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166034/
https://www.ncbi.nlm.nih.gov/pubmed/25158039
http://dx.doi.org/10.1021/bc500361d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166034/
https://www.ncbi.nlm.nih.gov/pubmed/25158039
http://dx.doi.org/10.1021/bc500361d

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