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Reduction-Sensitive Dual Functional Nanomicelles for Improved Delivery of Paclitaxel

[Image: see text] We have developed a dual-functional nanocarrier composed of a hydrophilic polyethylene glycol (PEG) and a hydrophobic farnesylthiosalicylate (FTS, a nontoxic Ras antagonist), which is effective in delivery of hydrophobic anticancer drug, paclitaxel (PTX). To facilitate the retentio...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolan, Liu, Ke, Huang, Yixian, Xu, Jieni, Li, Jiang, Ma, Xiaochao, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166038/
https://www.ncbi.nlm.nih.gov/pubmed/25121577
http://dx.doi.org/10.1021/bc500292j