Carbohydrate-to-carbohydrate interactions between α2,3-linked sialic acids on α2 integrin subunits and asialo-GM1 underlie the bone metastatic behaviour of LNCAP-derivative C4-2B prostate cancer cells

Complex interplays among proteins, lipids and carbohydrates can alter the phenotype and are suggested to have a crucial role in tumour metastasis. Our previous studies indicated that a complex of the GSLs (glycosphingolipids), AsGM1 (asialo-GM1), which lacks α2,3-linked sialic acid, and α2β1 integri...

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Detalles Bibliográficos
Autores principales: Van Slambrouck, Séverine, Groux-Degroote, Sophie, Krzewinski-Recchi, Marie-Ange, Cazet, Aurélie, Delannoy, Philippe, Steelant, Wim F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166120/
https://www.ncbi.nlm.nih.gov/pubmed/25137483
http://dx.doi.org/10.1042/BSR20140096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166120/
https://www.ncbi.nlm.nih.gov/pubmed/25137483
http://dx.doi.org/10.1042/BSR20140096

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