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Endothelial nitric oxide synthase is regulated by ERK phosphorylation at Ser(602)

eNOS (endothelial nitric oxide synthase) contains a MAPK (mitogen-activated protein kinase)-binding site associated with a major eNOS control element. Purified ERK (extracellular-signal-regulated kinase) phosphorylates eNOS with a stoichiometry of 2–3 phosphates per eNOS monomer. Phosphorylation dec...

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Detalles Bibliográficos
Autores principales: Salerno, John C., Ghosh, Dipak K., Razdan, Raj, Helms, Katy A., Brown, Christopher C., McMurry, Jonathan L., Rye, Emily A., Chrestensen, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166121/
https://www.ncbi.nlm.nih.gov/pubmed/25000310
http://dx.doi.org/10.1042/BSR20140015