Cargando…
Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer’s disease
Abnormal elevation of amyloid β-peptide (Aβ) levels in the brain is the primary trigger for neuronal cell death specific to Alzheimer’s disease (AD). It is now evident that Aβ levels in the brain are manipulable due to a dynamic equilibrium between its production from the amyloid precursor protein (...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166351/ https://www.ncbi.nlm.nih.gov/pubmed/25278875 http://dx.doi.org/10.3389/fnagi.2014.00235 |