New Insights into FAK Phosphorylation Based on a FAT Domain-Defective Mutation

Mounting evidence suggests that the FAK N-terminal (FERM) domain controls FAK phosphorylation and function; however, little is known regarding the role of the C terminal (FAT) domain in FAK regulation. We identified a patient-derived FAK mutant, in which a 27-amino acid segment was deleted from the...

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Detalles Bibliográficos
Autores principales: Fang, Xuqian, Liu, Xiangfan, Yao, Ling, Chen, Changqiang, Lin, Jiafei, Ni, Peihua, Zheng, Xinmin, Fan, Qishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166415/
https://www.ncbi.nlm.nih.gov/pubmed/25226367
http://dx.doi.org/10.1371/journal.pone.0107134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166415/
https://www.ncbi.nlm.nih.gov/pubmed/25226367
http://dx.doi.org/10.1371/journal.pone.0107134

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