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Detection of Serum Antibodies Cross-Reacting with Mycobacterium avium Subspecies paratuberculosis and Beta-Cell Antigen Zinc Transporter 8 Homologous Peptides in Patients with High-Risk Proliferative Diabetic Retinopathy

PURPOSE: MAP3865c, a Mycobacterium avium subspecies paratuberculosis (MAP) cell membrane protein, has a relevant sequence homology with zinc transporter 8 (ZnT8), a beta-cell membrane protein involved in Zn++ transportation. Recently, antibodies recognizing MAP3865c epitopes have been shown to cross...

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Detalles Bibliográficos
Autores principales: Pinna, Antonio, Masala, Speranza, Blasetti, Francesco, Maiore, Irene, Cossu, Davide, Paccagnini, Daniela, Mameli, Giuseppe, Sechi, Leonardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166466/
https://www.ncbi.nlm.nih.gov/pubmed/25226393
http://dx.doi.org/10.1371/journal.pone.0107802