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Genome-driven integrated classification of breast cancer validated in over 7,500 samples

BACKGROUND: IntClust is a classification of breast cancer comprising 10 subtypes based on molecular drivers identified through the integration of genomic and transcriptomic data from 1,000 breast tumors and validated in a further 1,000. We present a reliable method for subtyping breast tumors into t...

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Detalles Bibliográficos
Autores principales: Ali, H Raza, Rueda, Oscar M, Chin, Suet-Feung, Curtis, Christina, Dunning, Mark J, Aparicio, Samuel AJR, Caldas, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166472/
https://www.ncbi.nlm.nih.gov/pubmed/25164602
http://dx.doi.org/10.1186/s13059-014-0431-1