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MHC-I Molecules Selectively Inhibit Cell-Mediated Cytotoxicity Triggered by ITAM-Coupled Activating Receptors and 2B4

NK cell effector functions are controlled by a combination of inhibitory receptors, which modulate NK cell activation initiated by stimulatory receptors. Most of the canonical NK cell inhibitory receptors recognize allelic forms of classical and non-classical MHC class I molecules. Furthermore, high...

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Detalles Bibliográficos
Autores principales: Corral-San Miguel, Rubén, Hernández-Caselles, Trinidad, Ruiz Alcaraz, Antonio José, Martínez-Esparza, María, García-Peñarrubia, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166474/
https://www.ncbi.nlm.nih.gov/pubmed/25226085
http://dx.doi.org/10.1371/journal.pone.0107054