Cargando…

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

The HEK293 human cell lineage is widely used in cell biology and biotechnology. Here we use whole-genome resequencing of six 293 cell lines to study the dynamics of this aneuploid genome in response to the manipulations used to generate common 293 cell derivatives, such as transformation and stable...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yao-Cheng, Boone, Morgane, Meuris, Leander, Lemmens, Irma, Van Roy, Nadine, Soete, Arne, Reumers, Joke, Moisse, Matthieu, Plaisance, Stéphane, Drmanac, Radoje, Chen, Jason, Speleman, Frank, Lambrechts, Diether, Van de Peer, Yves, Tavernier, Jan, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166678/
https://www.ncbi.nlm.nih.gov/pubmed/25182477
http://dx.doi.org/10.1038/ncomms5767