Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

TAL-effector nucleases (TALENs) are attractive tools for sequence-specific genome modifications, but their delivery still remains problematic. It is well known that the presence of multiple sequence repeats in TALEN genes hampers the use of lentiviral vectors. We report that lentiviral vectors readi...

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Detalles Bibliográficos
Autores principales: Mock, Ulrike, Riecken, Kristoffer, Berdien, Belinda, Qasim, Waseem, Chan, Emma, Cathomen, Toni, Fehse, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166709/
https://www.ncbi.nlm.nih.gov/pubmed/25230987
http://dx.doi.org/10.1038/srep06409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166709/
https://www.ncbi.nlm.nih.gov/pubmed/25230987
http://dx.doi.org/10.1038/srep06409

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