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A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor

It was previously demonstrated that microRNA-199a (miR-199a) was down-regulated in testicular germ cell tumor (TGCT) partially caused by hypermethylation of its promoter. miR-199a is encoded by two loci in the human genome, miR-199a-1 on chromosome (Chr) 19 and miR-199a-2 on Chr 1. Both loci encode...

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Detalles Bibliográficos
Autores principales: Chen, Bi-Feng, Suen, Yick-Keung, Gu, Shen, Li, Lu, Chan, Wai-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166711/
https://www.ncbi.nlm.nih.gov/pubmed/25231260
http://dx.doi.org/10.1038/srep06413