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Molecular Docking of Known Carcinogen 4- (Methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) with Cyclin Dependent Kinases towards Its Potential Role in Cell Cycle Perturbation

Cell cycle is maintained almost all the times and is controlled by various regulatory proteins and their complexes (Cdk+Cyclin) in different phases of interphase (G(1), S and G(2)) and mitosis of cell cycle. A number of mechanisms have been proposed for the initiation and progression of carcinogenes...

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Detalles Bibliográficos
Autores principales: Haneef, Mohd, Lohani, Mohtashim, Dhasmana, Anupam, Jamal, Qazi M.S, Shahid, S.M.A, Firdaus, Sumbul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166773/
https://www.ncbi.nlm.nih.gov/pubmed/25258489
http://dx.doi.org/10.6026/97320630010526