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Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts

Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P. falciparum adaptation to human hosts by fully sequencing the genome of the closely related chimpanzee parasite species P. reichenowi, a...

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Detalles Bibliográficos
Autores principales: Otto, Thomas D., Rayner, Julian C., Böhme, Ulrike, Pain, Arnab, Spottiswoode, Natasha, Sanders, Mandy, Quail, Michael, Ollomo, Benjamin, Renaud, François, Thomas, Alan W., Prugnolle, Franck, Conway, David J., Newbold, Chris, Berriman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166903/
https://www.ncbi.nlm.nih.gov/pubmed/25203297
http://dx.doi.org/10.1038/ncomms5754