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Histone modifications and a choice of variant: a language that helps the genome express itself
Covalent post-translational modifications on histones impact chromatin structure and function. Their misfunction, along with perturbations or mutations in genes that regulate their dynamic status, has been observed in several diseases. Thus, targeting histone modifications represents attractive oppo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Faculty of 1000 Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166940/ https://www.ncbi.nlm.nih.gov/pubmed/25343033 http://dx.doi.org/10.12703/P6-76 |