Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia-ischemia

BACKGROUND: Hypoxic preconditioning (HPc) protects the neonatal brain in the setting of hypoxia-ischemia (HI). The mechanisms of protection may depend on activation of hypoxia inducible factor (HIF-1α). The present study sought to clarify the role of HIF-1α after HPc and HI. METHODS: To induce HPc,...

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Detalles Bibliográficos
Autores principales: Sheldon, R. Ann, Lee, Christina L., Jiang, Xiangning, Knox, Renatta N., Ferriero, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167022/
https://www.ncbi.nlm.nih.gov/pubmed/24713818
http://dx.doi.org/10.1038/pr.2014.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167022/
https://www.ncbi.nlm.nih.gov/pubmed/24713818
http://dx.doi.org/10.1038/pr.2014.53

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