Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting

Because the role of the viral B2 protein in the pathogenesis of nervous necrosis virus infection remains unknown, the aim of the present study was to determine the effects of B2 protein on hydrogen peroxide (H(2)O(2))-mediated cell death via mitochondrial targeting. Using a B2 deletion mutant, the B...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Yu C., Chiu, Hsuan W., Hung, Jo C., Hong, Jiann R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167032/
https://www.ncbi.nlm.nih.gov/pubmed/25008790
http://dx.doi.org/10.1007/s10495-014-1016-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167032/
https://www.ncbi.nlm.nih.gov/pubmed/25008790
http://dx.doi.org/10.1007/s10495-014-1016-x

Ejemplares similares