Direct Evidence of Catalytic Heterogeneity in Lactate Dehydrogenase by Temperature Jump Infrared Spectroscopy

[Image: see text] Protein conformational heterogeneity and dynamics are known to play an important role in enzyme catalysis, but their influence has been difficult to observe directly. We have studied the effects of heterogeneity in the catalytic reaction of pig heart lactate dehydrogenase using iso...

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Detalles Bibliográficos
Autores principales: Reddish, Michael J., Peng, Huo-Lei, Deng, Hua, Panwar, Kunal S., Callender, Robert, Dyer, R. Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167064/
https://www.ncbi.nlm.nih.gov/pubmed/25149276
http://dx.doi.org/10.1021/jp5050546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167064/
https://www.ncbi.nlm.nih.gov/pubmed/25149276
http://dx.doi.org/10.1021/jp5050546

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