Highly efficient genome editing via 2A-coupled co-expression of two TALEN monomers

BACKGROUND: Transcription activator-like effector nucleases (TALENs) are a useful tool for targeted gene editing. TALEN monomers are traditionally expressed from two different plasmids. Each encodes a different TALEN arm that binds to a user-defined sequence and mediates gene editing. Expression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Mariano, Andrew, Xu, Li, Han, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167141/
https://www.ncbi.nlm.nih.gov/pubmed/25204665
http://dx.doi.org/10.1186/1756-0500-7-628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167141/
https://www.ncbi.nlm.nih.gov/pubmed/25204665
http://dx.doi.org/10.1186/1756-0500-7-628

Ejemplares similares