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Highly efficient genome editing via 2A-coupled co-expression of two TALEN monomers
BACKGROUND: Transcription activator-like effector nucleases (TALENs) are a useful tool for targeted gene editing. TALEN monomers are traditionally expressed from two different plasmids. Each encodes a different TALEN arm that binds to a user-defined sequence and mediates gene editing. Expression of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167141/ https://www.ncbi.nlm.nih.gov/pubmed/25204665 http://dx.doi.org/10.1186/1756-0500-7-628 |