Cargando…
Enzymatic mono-pegylation of glucagon-like peptide 1 towards long lasting treatment of type 2 diabetes
Human glucagon-like peptide-1 (GLP-1) is a physiological gastrointestinal peptide with glucose-dependent insulinotropic effects which is therefore considered an interesting antidiabetic agent. However, after in vivo administration, exogenous GLP-1 does not exert its physiological action due to the c...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167179/ https://www.ncbi.nlm.nih.gov/pubmed/25755995 http://dx.doi.org/10.1016/j.rinphs.2012.09.001 |