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Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice

The mitochondrial targeted DNA repair enzyme, 8-oxoguanine DNA glycosylase 1, was previously reported to protect against mitochondrial DNA (mtDNA) damage and ventilator induced lung injury (VILI). In the present study we determined whether mitochondrial targeted endonuclease III (EndoIII) which clea...

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Detalles Bibliográficos
Autores principales: Hashizume, Masahiro, Mouner, Marc, Chouteau, Joshua M., Gorodnya, Olena M., Ruchko, Mykhaylo V., Wilson, Glenn L., Gillespie, Mark N., Parker, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167202/
https://www.ncbi.nlm.nih.gov/pubmed/25153040
http://dx.doi.org/10.3390/ph7080894