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Replicative Bypass of Abasic Site in Escherichia coli and Human Cells: Similarities and Differences

Abasic [apurinic/apyrimidinic (AP)] sites are the most common DNA damages, opposite which dAMP is frequently inserted (‘A-rule’) in Escherichia coli. Nucleotide insertion opposite the AP-site in eukaryotic cells depends on the assay system and the type of cells. Accordingly, a ‘C-rule’, ‘A-rule’, or...

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Detalles Bibliográficos
Autores principales: Weerasooriya, Savithri, Jasti, Vijay P., Basu, Ashis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167244/
https://www.ncbi.nlm.nih.gov/pubmed/25226389
http://dx.doi.org/10.1371/journal.pone.0107915