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Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case study

BACKGROUND: Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16). These compounds were designed to have improved bioavailability whe...

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Detalles Bibliográficos
Autores principales: Repsold, Lisa, Mqoco, Thandi, Wolmarans, Elize, Nkandeu, Sandra, Theron, Joji, Piorkowski, Tomek, du Toit, Peet, van Papendorp, Dirk, Joubert, Annie Margaretha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167501/
https://www.ncbi.nlm.nih.gov/pubmed/25299962
http://dx.doi.org/10.1186/0717-6287-47-39