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Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case study
BACKGROUND: Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16). These compounds were designed to have improved bioavailability whe...
Autores principales: | Repsold, Lisa, Mqoco, Thandi, Wolmarans, Elize, Nkandeu, Sandra, Theron, Joji, Piorkowski, Tomek, du Toit, Peet, van Papendorp, Dirk, Joubert, Annie Margaretha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167501/ https://www.ncbi.nlm.nih.gov/pubmed/25299962 http://dx.doi.org/10.1186/0717-6287-47-39 |
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