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Actinomyosin Contraction, Phosphorylation of VE-Cadherin, and Actin Remodeling Enable Melanoma-Induced Endothelial Cell-Cell Junction Disassembly

During melanoma cell extravasation through the vascular endothelium, melanoma cells interact with endothelial cells through secretion of cytokines and by adhesion between proteins displayed on opposing cell surfaces. How these tumor cell associated signals together regulate the dynamics of intracell...

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Detalles Bibliográficos
Autores principales: Weidert, Eric, Pohler, Steven E., Gomez, Esther W., Dong, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167543/
https://www.ncbi.nlm.nih.gov/pubmed/25225982
http://dx.doi.org/10.1371/journal.pone.0108092